Life in Lublin monastery began in the year 1426. The Bridgettines took care of the monastery and the church until 1835. During the period of their governments they have formed a charity association called Brotherhood of the poor aimed at providing material and moral assistance to the poor and they also carried out a number of thorough works that were intended to expand the temple and its surrounding buildings. The major achievements in this field have particularly had the abbess Agnieszka Jastkowska (1589-1630) and her successor Dorota Firlejówna (1632-1660). While the first one has focused on building, modernizing and rebuilding mainly buildings (at that time, three of the four wings of the monastery were built, a church tower and a choir; a chancel was rebuilt); the second abbess has concentrated mainly on changing the interior decoration of the church and important monastery areas ( the stalls were installed in the chancel choir,  five altars appeared, a new ambo and balustrades decorated with emblems). Money for the reconstruction and modernization of the church came mainly from the dowries of the nuns who were joining the convent in large numbers at that time. The recruitment was even limited, accepting only those ones that had a high dowry. Moreover, when Dorota Firlejówna was the abbess, the Firlej family also generously supported the convent.

After the year 1819 the Bridgettines were forbidden of admitting novices. In 1835, when the number of nuns declined to five, the government moved in to the large empty rooms of the Bridgettines' monastery, the Congregation of the Visitation Sisters that have been removed from their own buildings. The Visitandines during time of their stay in Lublin, established the fraternity of the Sweetest Heart of Jesus. They also ran a boarding school and a female school, and by celebrating services to the Heart of Jesus contributed to the increase of devotion among the congregation. This resulted in the new bloom of the church and the monastery in which people gathered to seek consolation, hope and power of spirit in the difficult times of partitions and annexations. After the fall of the January Uprising in 1864, the existing monasteries were abolished, and their property was taken over by the public treasury.

In the year 1870 the last abbess of the Bridgettines died. Five years later, the fraternity of the Heart of Jesus was abolished seeing  in their prayers, devotions and sermons threatening political aspects for the hostile government. In 1882 the Visitation Sisters were moved to Warsaw, all their possessions were confiscated, and without any funds the church was left to the local priest and the congregation. Thanks to their generosity and dedication, they managed to save the historic temple from destruction by making a general renovation in the years 1903-1910 for the 500th anniversary of Grunwald victory. The renovation was completed in 1934.